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What will my narcolepsy DNA test results tell me?

This genotype analysis will indicate whether or not you have the DQB1*06:02 allele that is associated with an increased risk of narcolepsy.

A positive result indicates that the HLA-DQB1*06:02 has been detected. A positive result includes both heterozygotes (who carry one copy of the DQB1*06:02 allele) and homozygotes (who carry two copies of the DQB1*06:02 allele). A positive result indicates an increased risk of narcolepsy and is supportive of a clinical diagnosis of narcolepsy. However, this result does not by itself establish a diagnosis.

A negative result indicates that HLA-DQB1*06:02 was not detected. This means that there is no increased risk of narcolepsy and a diagnosis of narcolepsy is less likely. However, this result does not eliminate a narcolepsy diagnosis.

Prognosis

As soon as gluten is removed from the diet, the intestines have a chance to heal. Children are generally symptom-free in 3-6 months, while adults may require 2-3 years. During this recovery period, symptoms often still occur despite no consumption of gluten, and nutrient supplement in alternative ways (e.g. IV) may be required to aid in the healing process. Very severe intestinal damage may never heal completely and other symptoms, including reduced growth or bone or dental damage, cannot be reversed.

 

DNA Narcolepsy Test

Determine if your genes increase your risk of narcolepsy.

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